Search Results

A Phase 3, randomized, open-label, multicenter, controlled study to evaluate the efficacy and safety of zanidatamab in combination with physician’s choice chemotherapy compared to trastuzumab in combination with physician’s choice chemotherapy for the treatment of participants with metastatic HER2-positive breast cancer who have progressed on, or are intolerant to, previous trastuzumab deruxtecan treatment (JZP598-303) MOA:…

A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) with or without Durvalumab compared with Investigator’s Choice of Chemotherapy (Paclitaxel/Nab-paclitaxel or Gemcitabine+ Carboplatin) in combination with Pembrolizumab in Patients with PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPIONBreast05) MOA: Anti-PD-1 monoclonal antibody, Anti-PD-L1 (CD274) monoclonal antibody, Platinum compound, Ribonucleotide reductase inhibitor,…

A Randomized, Double-blind, Placebo-controlled Phase 3 Study to evaluate Dostarlimab as Sequential Therapy after Chemoradiation in Patients with Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma MOA: Dostarlimab is a humanized anti-PD-1 IgG4 mAb. Key Eligibility Criteria: Unresected LA histologically confirmed HNSCC of the oral cavity,oropharynx (OPSCC), hypopharynx or larynx OPSCC p16 positive: T4…

Child and adult sitting together in front of a decorated Christmas tree. The holidays can be filled with celebrations and time spent with loved ones, but even in the best circumstances, it’s easy to feel overextended and anxious. Finding the balance between self-care and participation can put the focus on good health and cheer while…