Search Results

A phase 3 open-label, randomized, controlled study to evaluate the efficacy and safety of petosemtamab compared with investigator’s choice monotherapy treatment in previously treated patients with incurable, metastatic/recurrent head and neck squamous cell carcinoma (MCLA-158-CL02) MOA: Petosemtamab is a bispecific antibody targeting EGFR and LGR5 Key Eligibility Criteria: Metastatic or locally advanced HNSCC not amenable…

A Phase II, multicentre, multicohort, open-label trial to evaluate the efficacy and safety of oral zongertinib (BI 1810631) for the treatment of selected HER2-mutated or overexpressed/amplified solid tumours  MOA: Zongertinib is an EGFR wild-type sparing, selective HER2 inhibitor with potent inhibitory activity on all oncogenic HER2 mutations. Key Eligibility Criteria: Subjects with a previously treated,…

Randomized Phase 2b Study of ZEN003694 in Combination with Enzalutamide versus Enzalutamide Monotherapy in Patients with Metastatic Castration-Resistant Prostate Cancer (ZEN003694-201) MOA: ZEN003694 epigenetically regulates gene expression through bromodomain and extra-terminal domain (BET) inhibition. Key Eligibility Criteria: Metastatic, castration-resistant, histologically confirmed prostate cancer that has progressed on prior abiraterone treatment Patient must meet definition of…

Human papillomaviruses, or HPVs, are a group of more than 200 related viruses, some of which are linked to cancer. There are about 30 HPV types that can be easily passed between partners through sexual contact, and two of these viruses are responsible for more than 70 percent of cervical cancer cases. In addition to…

Lindsey is a Licensed Clinical Social Worker (LCSW-C) with over 15 years of experience working with oncology patients and their families. She is a certified oncology social worker (OSW-C) and has received specialized training in Meaning-Centered Psychotherapy. Lindsey has worked in diverse clinical environments, including both inpatient and outpatient care, and more recently, as an…