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A Phase 3 Randomized Double-blind Study of Adjuvant Pembrolizumab With or Without V940 in Participants With Resectable Stage II to IIIB (N2) NSCLC not Achieving pCR After Receiving Neoadjuvant Pembrolizumab With Platinum-based Doublet Chemotherapy (INTerpath-009) (V940-009) MOA: V940 is a lipid encapsulated mRNA based Individualized Neoantigen Therapy (INT) encoding neoantigens to induce specific T cells…

D702AC00001: A Randomized, Phase III Study of Rilvegostomig in Combination with Fluoropyrimidine and Trastuzumab Deruxtecan versus Trastuzumab, Chemotherapy, and Pembrolizumab for the First line Treatment of HER2-positive Gastric Cancer. (ARTEMIDE-Gastric01) MOA: Rilvegostomig is a bispecific antibody with an engineered triple-mutant Fc domain targeting PD-1 and TIGIT. Key Eligibility Criteria: Previously untreated, unresectable, locally advanced or…

Next-generation sequencing (NGS) results, treatment flexibility, and patient age must be carefully weighed to determine whether irinotecan liposome (Onivyde) plus oxaliplatin, 5-fluorouracil (5-FU), and leucovorin (NALIRIFOX) is an appropriate first-line treatment for patients with metastatic pancreatic cancer, according to Dong Kim, MD. The regimen received FDA approval for this population in February 2024.1 “One of the…

A Phase II Study Investigating Fruquintinib plus FOLFIRI as Second-Line Treatment for Participants with Metastatic Colorectal Cancer (mCRC) MOA: Fruquintinib is a highly selective and potent VEGFR inhibitor. Key Eligibility Criteria: Subjects must have confirmed mCRC Genetic aberrations are allowed, excludes MSI-H and BRAF V600 Subjects must have received 1L therapy that included oxaliplatin, afluoropyrimidine,…

Michaela is a licensed, board-certified genetic counselor with extensive experience in both clinical and research settings, particularly within the field of cancer genetics. She holds dual bachelor’s degrees in biology and psychology from the University of Maryland, College Park and a master’s degree in Genetic Counseling from Stanford University. Throughout her academic and professional journey,…

Yaquelin Guzman is a board-certified Physician Assistant committed to delivering evidence-based, compassionate care while fostering strong partnerships with patients, families, and the multidisciplinary oncology team. Her professional interests include patient education, symptom management, and optimizing continuity of care throughout the treatment journey. Before becoming a Physician Assistant, Yaquelin spent five years as a Radiation Therapist,…