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Phase 2 Single Arm Trial with a Safety Lead-in of Tucatinib in Combination with Doxil for the Treatment of HER2+ Metastatic Breast Cancer (BRE 381) MOA: Tucatinib is an oral tyrosine kinase inhibitor selective for HER2 Doxil is an anthracycline topoisomerase II inhibitor Key Eligibility Criteria: Women, men with HER2+ metastatic breast cancer (IHC3+ or…

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October 1, 2024

Understanding Mammogram Recalls Tech capturing image during a routine mammogram It is not unusual to get recalled after an initial screening mammogram. Additional imaging is often requested so that a clearer view of a particular area of breast tissue can be captured. Fewer than one in 10 women who return for additional testing are found…

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A Phase Ib/III, Open-label, Randomised Study of Capivasertib plus CDK4/6 Inhibitors and Fulvestrant versus CDK4/6 Inhibitors and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced, Unresectable or Metastatic Breast Cancer (CAPItello-292) MOA: Capivasertib is an oral pan-AKT inhibitor Key Eligibility Criteria: Men and women with adv/metastatic HR+/HER2- breast cancer Pre-/perimenopausal…

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A Phase III, Randomized, Open-Label, Multi-Center, Global Study of Volrustomig as Sequential Therapy Versus Observation in Participants with Unresected Locally Advanced-Head and Neck Squamous Cell Carcinoma (LA-HNSCC) Who Have Not Progressed Following Definitive Concurrent Chemoradiotherapy  (eVOLVE-HNSCC) MOA: Checkpoint inhibitor Volrustomig (MEDI5752): Monovalent, bispecific, anti-PD-1 / anti-CTLA-4 humanized IgG1 mAb Key Eligibility Criteria: Locally advanced squamous…

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Marissa Davidson, DNP, earned her associate degree in nursing at Morrisville State University, where she was awarded the Distinguished Nurse Award for academic excellence. She then went on to earn a bachelor’s degree in nursing at Chamberlain University. In May 2024, she graduated from the University of Maryland School of Nursing with a Doctor of…

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