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Solid Tumors
Clinical Trial Search
Trial Protocol ID
MCLA-128-CL01_eNRGy *RIT*
A Phase I/II Study of MCLA-128, a Full Length IgG1 Bispecific Antibody Targeting HER2 and HER3, in Patients With Solid Tumors (eNRGy)
Trial Protocol ID
1403-0002 *RIT*
A phase Ia/Ib, open-label, dose escalation study of the combination of BI 907828 with BI 754091 (ezabenlimab) and BI 754111 and the combination of BI 907828 with BI 754091 (ezabenlimab) followed by expansion cohorts, in patients with advanced solid tumors
Trial Protocol ID
1403-0001 *RIT*
A Phase Ia/Ib, Open Label, Multicenter, Dose-escalation Study of BI 907828 (Brigimadlin) in Patients With Advanced or Metastatic Solid Tumors
Trial Protocol ID
1403-0011_Brightline 2 *RIT*
Brightline 2 - A Phase II/III, open-label, single-arm, multi-centre trial of BI 907828 for treatment of patients with locally advanced/metastatic, MDM2 amplified, TP53 wild-type solid tumours-biliary tract adenocarcinoma, pancreatic ductal adenocarcinoma, or other selected solid tumors
Trial Protocol ID
IK930-001 *RIT*
A Phase 1, First-in-Human Study of IK-930, an Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors
Trial Protocol ID
TPX-0005-07 *RIT*
A Phase 1/2, Open-Label, Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity Study of Repotrectinib in Pediatric and Young Adult Subjects With Advanced or Metastatic Malignancies Harboring ALK, ROS1, NTRK1-3 Alterations
Trial Protocol ID
F8394-201a *RIT*
A Phase 2 Master Protocol to assess the efficacy and safety of FORE8394, an inhibitor of BRAF class 1 and class 2 alterations, in participants with cancer harboring BRAF alterations
Trial Protocol ID
BO41932_TAPISTRY
Investigator
Frederick Min, M.D.
Tumor-Agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Phase II Platform Trial
Trial Protocol ID
USOR 22052_TSC-007 *STAR*
A Phase 2 multi-center open-label basket trial of nab-sirolimus for adult and adolescent patients with malignant solid tumors harboring pathogenic inactivating alterations in TSC1 or TSC2 genesĀ
Trial Protocol ID
USOR 19151_849-001 *STAR*
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation
Trial Protocol ID
USOR 22093_XB002-101_Jewel-101
Investigator
Yousuf A. Gaffar, M.D.
A DOSE-ESCALATION AND EXPANSION STUDY OF THE SAFETY AND PHARMACOKINETICS OF XB002 AS SINGLE-AGENT AND COMBINATION THERAPY IN SUBJECTS WITH INOPERABLE LOCALLY ADVANCED OR METASTATIC SOLID TUMORS (XB002-101)
Trial Protocol ID
USOR 21367_GRAIL-012
Investigator
Jason Taksey, M.D.
The PATHFINDER 2 Study: Evaluating the Safety and Performance of the GRAIL Multi-Cancer Early Detection Test in an Eligible Screening Population
Trial Protocol ID
APL-101-01_SPARTA
Investigator
Kashif Ali, M.D.
Phase 1 / 2 Multicenter Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of APL-101 in Subjects with Non-Small Cell Lung Cancer with c-Met Exon 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Trial Protocol ID
USOR 18283_IMMU-132-06_TROPHY U-01
Investigator
Jun Sun, M.D.
A Phase II Open-Label Study of Sacituzumab Govitecan in Unresectable
Locally Advanced/Metastatic Urothelial Cancer
Trial Protocol ID
USOR 18283_IMMU-132-06_TROPHY U-01
Investigator
Jun Sun, M.D.
A Phase II Open-Label Study of Sacituzumab Govitecan in Unresectable
Locally Advanced/Metastatic Urothelial Cancer
Trial Protocol ID
MK 3475-158_KEYNOTE-158
Investigator
John Wallmark, M.D.
A Clinical Trial of Pembrolizumab (MK-3475) Evaluating Predictive Biomarkers in Subjects with Advanced Solid Tumors (KEYNOTE-158)
Trial Protocol ID
RGX-104-001
Investigator
John Wallmark, M.D.
A Phase 1 Study of RGX-104, a Small Molecule LXR Agonist, as a Single Agent and as Combination Therapy in Patients with Advanced Solid Malignancies and Lymphoma with an Expansion in Select Malignancies
Trial Protocol ID
BO41932_TAPISTRY
Investigator
Frederick Min, M.D.
TUMOR-AGNOSTIC PRECISION IMMUNO-ONCOLOGY AND SOMATIC TARGETING RATIONAL FOR YOU (TAPISTRY) PHASE II PLATFORM TRIAL
Trial Protocol ID
GCT1042-01
Investigator
Mohit Narang, M.D.
A First-in-Human, Open-label, Dose-escalation Trial With Expansion Cohorts to Evaluate Safety and Anti-tumor Activity of GEN1042 in Subjects With Malignant Solid Tumors