Blood disorders encompass a wide range of conditions that affect the components and functions of blood. These disorders can be inherited or acquired, and they may impact red blood cells, white blood cells, platelets, plasma, or the bone marrow.

Red Blood Cell Disorders

These affect the cells responsible for carrying oxygen throughout the body.

  • Anemia (e.g., iron-deficiency, pernicious, aplastic, autoimmune hemolytic)
  • Sickle Cell Disease
  • Thalassemia
  • Polycythemia Vera (overproduction of red cells)

White Blood Cell Disorders

These impact the immune system and its ability to fight infections.

  • Leukemia (a type of blood cancer)
  • Lymphoma
  • Neutropenia (low neutrophil count)
  • Leukocytosis (high white cell count)

Platelet Disorders

Platelets help blood clot; disorders here affect bleeding and clotting.

  • Thrombocytopenia (low platelet count)
  • Thrombocythemia (high platelet count)
  • Idiopathic Thrombocytopenic Purpura (ITP)
  • Thrombotic Thrombocytopenic Purpura (TTP)

Clotting Disorders

These involve problems with clotting factors or proteins in the blood.

  • Hemophilia (types A, B, C)
  • Von Willebrand Disease
  • Factor V Leiden
  • Antiphospholipid Syndrome
  • Protein C/S Deficiency
  • Antithrombin Deficiency

Plasma Disorders

Plasma is the liquid part of blood; disorders here affect its viscosity or protein content.

  • Hyperviscosity Syndrome
  • Cryoglobulinemia
  • Amyloidosis
  • Benign Monoclonal Gammopathy

Bone Marrow Disorders

These affect the production of blood cells.

  • Aplastic Anemia
  • Myelodysplastic Syndromes
  • Myeloproliferative Neoplasms (e.g., myelofibrosis, chronic myelogenous leukemia)

Iron Metabolism Disorders

These affect how the body processes iron.

  • Hemochromatosis